Before Tony threw his armor into the ocean, Dr. Doom invaded the city. Now Iron Man and the War Machine has to stop Dr. Doom.
- Tony Stark / Iron Man - The main character of the anime movie. He almost threw his armor into the ocean.
- Rhodney / War Machine - He is now employed to Stark International and at the end of the movie, he became Iron Man.
- Pepper Potts - The-now-wife of Tony and at the end of the movie, she became the War Machine.
- Ho Yinsen - The hardware maker of Stark International. He was killed by Doom when he found the first Iron Man armor (Tales of Suspense #39-#48)
- Dr. Doom - The main villain of the anime movie and was killed by Iron Man 2 (Rhodney) when Ho was killed.